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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
23.94
Human Site:
S424
Identified Species:
37.62
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
S424
L
F
R
N
D
Q
N
S
S
G
E
P
E
Y
S
Chimpanzee
Pan troglodytes
XP_523125
963
104993
S424
L
F
R
N
D
Q
N
S
S
G
E
P
E
Y
S
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
S425
L
F
R
N
D
Q
N
S
S
G
E
P
E
Y
S
Dog
Lupus familis
XP_532364
964
105327
N425
L
F
R
H
D
Q
D
N
S
G
E
P
T
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
S425
L
F
R
N
D
E
N
S
S
E
P
E
Y
S
Q
Rat
Rattus norvegicus
Q62751
963
104783
S425
L
F
R
N
D
E
N
S
S
E
P
E
Y
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
S472
L
F
R
N
N
D
S
S
S
E
E
P
E
Y
S
Chicken
Gallus gallus
Q5ZLQ4
965
105344
S426
L
F
R
N
G
E
S
S
S
R
E
P
E
Y
S
Frog
Xenopus laevis
Q6NTP2
955
104418
Q418
L
L
R
Q
E
N
V
Q
Q
P
L
Y
S
K
V
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
D385
S
G
P
K
R
P
Q
D
R
V
A
I
T
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
P385
S
V
S
G
P
K
R
P
H
D
R
V
S
V
S
Honey Bee
Apis mellifera
XP_392993
890
98796
V385
P
H
D
R
V
S
V
V
D
M
K
I
D
F
K
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
Q386
V
E
L
A
S
L
A
Q
D
F
S
K
G
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
S395
E
M
K
A
D
W
H
S
C
L
D
N
R
V
G
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
C280
A
T
G
M
G
T
I
C
N
M
G
A
E
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
53.3
53.3
N.A.
73.3
73.3
13.3
0
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
60
60
N.A.
86.6
86.6
20
0
N.A.
13.3
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
14
0
0
7
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
47
7
7
7
14
7
7
0
7
0
0
% D
% Glu:
7
7
0
0
7
20
0
0
0
20
40
14
40
0
0
% E
% Phe:
0
54
0
0
0
0
0
0
0
7
0
0
0
7
0
% F
% Gly:
0
7
7
7
14
0
0
0
0
27
7
0
7
7
14
% G
% His:
0
7
0
7
0
0
7
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
14
0
7
0
% I
% Lys:
0
0
7
7
0
7
0
0
0
0
7
7
0
7
7
% K
% Leu:
60
7
7
0
0
7
0
0
0
7
7
0
0
7
0
% L
% Met:
0
7
0
7
0
0
0
0
0
14
0
0
0
0
7
% M
% Asn:
0
0
0
47
7
7
34
7
7
0
0
7
0
0
0
% N
% Pro:
7
0
7
0
7
7
0
7
0
7
14
40
0
0
0
% P
% Gln:
0
0
0
7
0
27
7
14
7
0
0
0
0
0
14
% Q
% Arg:
0
0
60
7
7
0
7
0
7
7
7
0
7
0
0
% R
% Ser:
14
0
7
0
7
7
14
54
54
0
7
0
14
14
47
% S
% Thr:
0
7
0
0
0
7
0
0
0
0
0
0
14
0
7
% T
% Val:
7
7
0
0
7
0
14
7
0
7
0
7
0
14
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
14
40
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _